Anno 1602: Humble beginnings.
If you push me, I'll confess - I'm an Anno fan.
An often overlooked franchise, Anno came from rather humble beginnings back in 1998, with the European release of Anno 1602, which somehow became 1602 A.D. by the time it was released down under. Perhaps German publishers Sunflowers didn't think anyone outside Europe knew what "anno" referred to, or perhaps their translator got a bit carried away - it did little to detract from what was an unbelievably complex and, at times, overwhelming real-time strategy title.
Where the Anno games differ from virtually every other real-time strategy title out there is the emphasis on economic growth.